Microbrains Lab: Modeling NeurodegenerationSummer Course

Major Discipline(s)
Biology, Biomedicine / Biotechnology, Neuroscience
Location: Copenhagen
Labs, Research, & Practicums Session

In our aging society, more and more people suffer from neurodegenerative diseases such as Alzheimer’s disease (AD). Decades of research have focused on mouse models, but all drug candidates that have successfully treated AD in mice have failed in human clinical trials. In order to address these pressing needs, human models such as neurons, astrocytes, and microglia derived from induced pluripotent stem cells are the key. In combination with gene editing using CRISPR-Cas9 these cellular models provide insights into early disease development and progression in the species we need to investigate: humans.

Note: Reading materials regarding important molecular biology and/or genetics concepts needed for the course will be available before semester start so students can consult or study them if in doubt. Additionally, students will have the needed supervision for being able to perform the techniques.


Kristine Freude

DIS Summer Faculty

Professor in Cell Biology and Biochemistry, University of Copenhagen

MSc at Robert Koch Institute and Free University, Berlin, Germany, in 2001 working with Mycobacteria. PhD at Max Planck Institute for Molecular Genetics and Free University, Berlin, Germany in Human Genetics (2005). Postdoctoral Research Fellow at UC Irvine, CA, USA (2005-2011) Postdoctoral Researcher (2012-2014) University Copenhagen. Assistant Professor (2014-2015) University Copenhagen. Associate Professor (2015-2022), Professor since 2023, University Copenhagen. With DIS since 2016.