Introduction to the topic
Mesenchymal stem cells (MSCs) and their extracellular vesicles (EVs) are at the forefront of regenerative medicine due to their remarkable therapeutic potential. MSCs are multipotent stromal cells capable of differentiating into various regenerative cell types, with promising applications as MSC-based therapies for a range of diseases. EVs are small particles released by cells that mediate many of the therapeutic effects of MSCs, making them a promising tool for cell-free therapies.
Project details
This research project explores the mechanisms by which MSCs and their EVs promote tissue regeneration, with a particular emphasis on angiogenesis (formation of new blood vessels) and neurogenesis (generation of new neurons). Students will participate in a multidisciplinary investigation, ranging from molecular biology techniques to the analysis of cell behavior in vitro and potentially in vivo. The outcomes of this research may facilitate the development of innovative cell-free therapies for complex diseases and injuries, including those affecting the nervous and circulatory systems. This project offers a unique opportunity to gain hands-on experience in cutting-edge biomedical research and contribute to advances with real-world impact for patients.
Students will engage in laboratory work, including cell culture, EV isolation, and functional assays such as tube formation and neurite outgrowth. They will analyze and interpret experimental data, review relevant literature, prepare a research paper, and present their findings. Participants will gain practical skills in laboratory techniques, data analysis, and scientific communication while collaborating in a multidisciplinary international research environment. As the project spans multiple semesters, not all students will participate in every experimental phase.
Research Assistantship Hours
You will spend 180 hours directly engaged in research, together with 20 hours in co-curricular activities, during your RAship.
Field Studies: Culture & Language
As a co-curricular complement to your summer research, you will meet every Wednesday, together with faculty from the DIS European Humanities program, for a 6-week introduction to culture and language in Copenhagen.
Syllabus
Prerequisites
One year of biology including molecular biology at the university level. Recommended lab skills include cell culture, microscopy, and basic data analysis.
Additional application required
You will need to submit an additional research application through the Student Registration in order to enroll in this course.
Before you submit your research application, you must already be admitted to DIS.
All application materials must be submitted by 23:59 Central European Time on March 15.
Faculty
Reza Yarani
FacultyPh.D (Cellular and Genetic Medicine, Department of Cellular and Molecular Biology, University of Copenhagen, 2016). Assistant Professor, Translational Type 1 Diabetes Research, Department of Clinical Research, Steno Diabetes Center Copenhagen, 2021-Present. With DIS since 2023.
More information about your Research Assistantship
Learn more about the Labs, Research, and Practicums Summer Session.