Research Assistant: Identifying Neurobiological Changes in Individuals with High Familial Risk of Bipolar DisorderSummer Course

Major Discipline(s)
Neuroscience, Pre-Medicine / Health Science, Biology
Location: Copenhagen
Lab & Research Session

Location: Psychiatric Center Copenhagen, Copenhagen University Hospital, Rigshospitalet

Research topic: Bipolar disorder is associated with a wide range of neurobiological disturbances, including anomalies in the structure and function of cortical and subcortical brain regions. Recent studies have shown that many of these abnormalities are also present in never-depressed offspring of adults suffering from depression who are at increased risk of onset of this disorder. Identifying neurobiological changes in these individuals at high familial risk can provide a neural marker of depression risk and may facilitate the development of targeted strategies for the prevention and treatment of major depression.

What you will work with: The project is planned to involve visual assessment of the quality of MRI brain scans and brain models automatically constructed by the Freesurfer software and correct errors in the reconstruction. In addition, the project may also involve exploring recent neuroimaging literature in bipolar disorder and high-risk participants and summarizing these findings in a working document.


Julian Macoveanu

DIS Summer Faculty

Ph.D. (Medical Sciences (Neuroscience), Karolinska Institute, Sweden, 2006). Ph.D. Licentiate of Engineering (Computational Biology), University of Linköping, Sweden, 2005) MSc. (Biochemistry, Stockholm University, 2002). Postdoctoral Research Associate, Danish Research Center for Magnetic Resonance (DRCMR) Copenhagen University Hospital Hvidovre. With DIS since 2014.