Research Assistant: Health Technology, Brain Plasticity, Epilepsy, and ElectroencephalographySemester Course

Research Assistant Health Technology, Brain Plasticity, Epilepsy, and Electroencephalography
Major Discipline(s)
Biology, Neuroscience, Pre-Medicine / Health Science
Type
Elective Course
Available
Fall semester
Credit(s)
6

The research in Troels Kjær’s department focuses on health technology, brain plasticity, epilepsy, and electroencephalography.

Three Distinct Research Assistant Roles

Several types of Research Assistantships are offered depending on your background. You will either have the opportunity to do a literature study, a dry lab study at the computer, or participate in the ongoing clinical studies of the group.

  1. The research is currently involved in developing small implantable devices for EEG monitoring 24/7 for months. As a Research Assistant, you would be the first to describe how spikes or sleep varies in our individual patients. It is well-known that sleep pattern varies monthly with the moon and menstrual cycle, but there seem to be other types of periodicity.
  2. Troels Kjær’s department is building two tech-towns. The idea is to measure the effect of health technology in healthy subjects and patients with various specified diseases. This option is for you to do a proof of concept registration on yourself, do literature studies, and when the project is well on its way, do data-driven investigations.
  3. Large amounts of data are available in thousands of EEG recording in their database. Troels’ department is currently building tools to access parts of these data. As a Research Assistant, you can work mainly with data extraction or focus on academic questions such as how posterior dominant rhythm varies with age in our patients or the relation between eye closure and photoparoxystic activity.

References

  • Weisdorf S, Gangstad SW, Duun-Henriksen J, Mosholt KSS, Kjaer TW. High similarity between EEG from subcutaneous and proximate scalp electrodes in patients with temporal lobe epilepsy. J Neurophysiol. 2018 Jul 11. PubMed PMID: 29995605.
  • Zibrandtsen IC, Kidmose P, Kjaer TW. Detection of generalized tonic-clonic seizures from ear-EEG based on EMG analysis. Seizure. 2018 May 4;59:54-9. PubMed PMID: 29747022.
    Larsen LH, Zibrandtsen IC, Wienecke T, Kjaer TW, Langberg H, Nielsen JB, Christensen MS. Modulation of task-related cortical connectivity in the acute and subacute phase after stroke. The European journal of neuroscience. 2018 Feb 21. PubMed PMID: 29465793.
  • Foged MT, Vinter K, Stauning L, Kjaer TW, Ozenne B, Beniczky S, Paulson OB, Madsen FF, Pinborg LH, Danish Epilepsy Surgery G. Verbal learning and memory outcome in selective amygdalohippocampectomy versus temporal lobe resection in patients with hippocampal sclerosis. Epilepsy & behavior : E&B. 2018 Feb;79:180-7. PubMed PMID: 29306849.
  • Zibrandtsen IC, Kidmose P, Christensen CB, Kjaer TW. Ear-EEG detects ictal and interictal abnormalities in focal and generalized epilepsy – A comparison with scalp EEG monitoring. Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology. 2017 Oct 12;128(12):2454-61. PubMed PMID: 29096220.
  • Larsen LH, Zibrandtsen IC, Wienecke T, Kjaer TW, Christensen MS, Nielsen JB, Langberg H. Corticomuscular coherence in the acute and subacute phase after stroke. Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology. 2017 Sep 22;128(11):2217-26. PubMed PMID: 28987993.
  • Kjaer TW, Sorensen HBD, Groenborg S, Pedersen CR, Duun-Henriksen J. Detection of Paroxysms in Long-Term, Single-Channel EEG-Monitoring of Patients with Typical Absence Seizures. IEEE journal of translational engineering in health and medicine. 2017;5:2000108. PubMed PMID: 29018634. Pubmed Central PMCID: 5477700.
  • Schmidt LS, Kjaer TW, Schmiegelow K, Born AP. EEG with extreme delta brush in young female with methotrexate neurotoxicity supports NMDA receptor involvement. European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society. 2017 Sep;21(5):795-7. PubMed PMID: 28655493.
  • Kjaer TW, Hogenhaven H, Lee AP, Madsen FF, Jespersen B, Brennum J, Derm L, Moltke FB. Pharmacodynamics of remifentanil. Induced intracranial spike activity in mesial temporal lobe epilepsy. Epilepsy research. 2017 Jul;133:41-5. PubMed PMID: 28414967.

 

Related Discipline(s)

This course would also be of interest to the following discipline(s):
Biomedicine / Biotechnology

Faculty

Troels Wesenberg Kjær

DIS Copenhagen Semester Faculty

M.D. (University of Copenhagen, 1992). Ph.D. (University of Copenhagen, 1996). Chief Physician, Clinical Neurophysiology, Neurophysiology Center, Dept of Neurology, Roskilde University Hospital. With DIS since 2003.

Medical Practice & Policy, Troels Wesenberg Kjær